Analyzing splice variants with SGSeq

Alternative splicing is a process by which different variants of a gene are produced from a single primary transcript. This process allows you to generate multiple different proteins from a single gene, increasing the functional diversity of the genome. Alternative splicing can be regulated by different mechanisms, including cis-acting elements in the primary transcript and trans-acting factors that bind to these elements.

Analyzing alternative splicing in genomics can be beneficial in several ways, including allowing you to understand the genetic basis of disease. Many diseases are caused by mutations in genes that lead to changes in protein function. Alternative splicing can create different variants of a protein with different functions, and understanding how these variants are regulated can provide insights into disease mechanisms. The SGSeq R Bioconductor package can be used to help us analyze alternatively spliced transcripts. This package...